Michael R. Taylor, PhD
Assistant Member, Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital
Research: “Uncovering the Role of L-type Voltage-dependent Calcium Channels in The Formation of Photoreceptor Synaptic Ribbons”
Research
- Mechanisms of synaptic transmission
- Development of pediatric disease models
- Identification of biologically-active compounds
Publications
Baraban SC, Dinday MT, Castro PA, Chege S, Guyenet S, Taylor MR. A large-scale mutagenesis screen to identify seizure-resistant zebrafish. Epilepsia 48:1151-7, 2007.
Kennedy BN, Alvarez Y, Brockerhoff SE, Stearns GW, Sapetto-Rebow B, Taylor MR, Hurley JB. Identification of a zebrafish cone photoreceptor-specific promoter and genetic rescue of achromatopsia in the nof mutant. Invest Ophthalmol Vis Sci 48:522-9, 2007.
Baraban SC, Taylor MR, Castro PA, Baier H. Pentylenetetrazole induced changes in zebrafish behavior, neural activity, and c-fos expression. Neuroscience 131:759-68, 2005.
Taylor MR, Kikkawa S, Ramamurthy V, Kawakami K, Brockerhoff SE.The Zebrafish pob gene encodes a novel protein required for survival of red cone photoreceptor cells. Genetics 170:263-73, 2005.
Taylor MR, Hurley JB, Van Epps HA, Brockerhoff SE. A zebrafish model for pyruvate dehydrogenase deficiency: rescue of neurological dysfunction and embryonic lethality using a ketogenic diet. Proc Natl Acad Sci USA 101:4584-9, 2004.
Brockerhoff SE, Rieke F, Matthews HR, Taylor MR, Cilluffo MC, Fain GL, Ankoudinova I, Xiao M, Niemi GA, Tucker CL, Hurley JB. Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and a suppression of current in cones from the zebrafish mutant nof. J. Neurosci. 23:470-80, 2003.
Taylor MR, Van Epps HA, Kennedy MJ, Saari JC, Hurley JB, Brockerhoff SE. Biochemical analysis of phototransduction and visual cycle in zebrafish larvae. Methods in Enzymology 316:536-57, 2000.
Newburg DS, Peterson JA, Ruiz-Palacios GM, Matson DO, Morrow AL, Shults J, Guerrero MD, Chaturvedi P, Newburg SO, Scallan CD, Taylor MR, Ceriani RL, Pickering LK. Role of human-milk lactadherin in protection against symptomatic rotavirus infection. Lancet 351:1160-4, 1998.
Taylor MR, Couto JR, Scallan CD, Ceriani RL, Peterson JA. Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion. DNA Cell Biol 16:861-9. 1997.
Taylor MR, Peterson JA, Ceriani RL, Couto JR. Cloning and sequence analysis of human butyrophilin reveals a potential receptor function. Biochim Biophys Acta 1306:1-4, 1996.
Couto JR, Taylor MR, Godwin SG, Ceriani RL, Peterson JA. Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain. DNA Cell Biol 15:281-6, 1996.
Peterson JA, Couto JR, Taylor MR, Ceriani RL. Selection of tumor-specific epitopes on target antigens for radioimmunotherapy of breast cancer. Cancer Res 55:5847-51, 1995.
Last updated: May 2008
Kennedy BN, Alvarez Y, Brockerhoff SE, Stearns GW, Sapetto-Rebow B, Taylor MR, Hurley JB. Identification of a zebrafish cone photoreceptor-specific promoter and genetic rescue of achromatopsia in the nof mutant. Invest Ophthalmol Vis Sci 48:522-9, 2007.
Baraban SC, Taylor MR, Castro PA, Baier H. Pentylenetetrazole induced changes in zebrafish behavior, neural activity, and c-fos expression. Neuroscience 131:759-68, 2005.
Taylor MR, Kikkawa S, Ramamurthy V, Kawakami K, Brockerhoff SE.The Zebrafish pob gene encodes a novel protein required for survival of red cone photoreceptor cells. Genetics 170:263-73, 2005.
Taylor MR, Hurley JB, Van Epps HA, Brockerhoff SE. A zebrafish model for pyruvate dehydrogenase deficiency: rescue of neurological dysfunction and embryonic lethality using a ketogenic diet. Proc Natl Acad Sci USA 101:4584-9, 2004.
Brockerhoff SE, Rieke F, Matthews HR, Taylor MR, Cilluffo MC, Fain GL, Ankoudinova I, Xiao M, Niemi GA, Tucker CL, Hurley JB. Light stimulates a transducin-independent increase of cytoplasmic Ca2+ and a suppression of current in cones from the zebrafish mutant nof. J. Neurosci. 23:470-80, 2003.
Taylor MR, Van Epps HA, Kennedy MJ, Saari JC, Hurley JB, Brockerhoff SE. Biochemical analysis of phototransduction and visual cycle in zebrafish larvae. Methods in Enzymology 316:536-57, 2000.
Newburg DS, Peterson JA, Ruiz-Palacios GM, Matson DO, Morrow AL, Shults J, Guerrero MD, Chaturvedi P, Newburg SO, Scallan CD, Taylor MR, Ceriani RL, Pickering LK. Role of human-milk lactadherin in protection against symptomatic rotavirus infection. Lancet 351:1160-4, 1998.
Taylor MR, Couto JR, Scallan CD, Ceriani RL, Peterson JA. Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion. DNA Cell Biol 16:861-9. 1997.
Taylor MR, Peterson JA, Ceriani RL, Couto JR. Cloning and sequence analysis of human butyrophilin reveals a potential receptor function. Biochim Biophys Acta 1306:1-4, 1996.
Couto JR, Taylor MR, Godwin SG, Ceriani RL, Peterson JA. Cloning and sequence analysis of human breast epithelial antigen BA46 reveals an RGD cell adhesion sequence presented on an epidermal growth factor-like domain. DNA Cell Biol 15:281-6, 1996.
Peterson JA, Couto JR, Taylor MR, Ceriani RL. Selection of tumor-specific epitopes on target antigens for radioimmunotherapy of breast cancer. Cancer Res 55:5847-51, 1995.
Last updated: May 2008
